Interaction of Silver Nanoparticles With Tacaribe Virus

Silver nanoparticles possess many unique properties that make them attractive for use in biological applications. An area that has been largely unexplored is the interaction of nanomaterials with viruses and the possible use of silver nanoparticles as an antiviral agent. This research focuses on evaluating the interaction of silver nanoparticles with a New World arenavirus, Tacaribe virus, to determine if they influence viral replication. This suggests that the mode of action of viral neutralization by silver nanoparticles occurs during the early phases of viral replication.

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Mode of Antiviral Action of Silver Nanoparticles Against HIV-1

Silver nanoparticles have proven to exert antiviral activity against HIV-1 at non-cytotoxic concentrations, but the mechanism underlying their HIV-inhibitory activity has not been not fully elucidated. In this study, silver nanoparticles are evaluated to elucidate their mode of antiviral action against HIV-1 using a panel of different in vitro assays.

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Nanosilver Heals Inflammation from Contact Dermatitis

According to a study published in the journal Nanomedicine, in 2008, titled “Anti-inflammatory activity of nanocrystalline silver in a porcine contact dermatitis model,” researchers found that when dermatitis was induced in animals (i.e., pigs) the redness and swelling returned to near-normal after 72 hours of treatment with nanosilver, while groups treated with saline or with 0.5% silver nitrate (a caustic chemical compound of silver) remained inflamed.

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Nanosilver Heals Liver Damaged by Powerful Toxin

Researchers from the Department of Environmental Biotechnology, Bharathidasan University, India, have demonstrated in an animal study that small amounts of silver can help heal liver damage caused by a particularly harsh liver toxin. The study is titled “Hepatocurative activity of biosynthesized silver nanoparticles fabricated using Andrographis paniculata,” and it was published in the journal Colloids and Surfaces B, Biointerfaces, in February 2013.

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Nanosilver Kills Food-Borne Pathogens at Low Concentrations

According to this clinical study published in the International Food Resource Journal in 2011, titled, “A study on the minimum inhibitory concentration and minimum bactericidal concentration of Nano Colloidal Silver on food-borne pathogens,” researchers found that “Nano colloidal silver can be a potential antimicrobial agent due to its low cost of production and high effectiveness in antimicrobial properties, which may find wide applications in various food industries to address food safety issues…Ten different concentration of Nano Colloidal Silver were tested against Listeria monocytogenes, Escherichia coli O157:H7, Salmonella enterica Serovar Typhi, Vibrio cholera, Vibrio parahaemolyticus, Bacillus cereus and Staphylococcus aureus…”

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Nanosilver Kills Tuberculosis Pathogen at Low Levels

A clinical study titled “Fabrication of Silver Nanoparticles and Their Antimicrobial Mechanisms,” published in 2006 in the journal European Cells and Materials (Vol. 11), demonstrated that silver nanoparticles at a concentration of only 10 ppm was effective against Mycobacterium tuberculosis.

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Nanosilver Non-Toxic in New Human Clinical Study

In a brand new clinical study titled “In vivo Human Time-exposure Study of Orally Dosed Commercial Silver Nanoparticles,” published in October 2014 in the journal Nanomedicine, clinical researchers from the University of Utah demonstrated the lack of toxicity to humans of orally-ingested nanoscale colloidal silver at both 10 ppm and 32 ppm concentrations.

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Nanosilver Stops Activation of Nasal Polyp Epithelial Cells

Here’s some potentially good news for people suffering from nasal polyps – a relatively new clinical study published in the journal International Immunopharmacology in November 2011, demonstrated that nanosilver has significant anti-inflammatory affects on “respiratory epithelial cell inflammation,” meaning it stops the cells of nasal polyps from becoming inflamed.

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Nanotechnology’s Latest Oncolytic Agent: Silver, Cancer & Infection Associations (Part III) By John Apsley, DC, Kent Holtorf, MD, Eric Gordon, MD, Wayne Anderson, ND, and Rashid Buttar, DO

Landmark studies over the past several decades have demonstrated that oligodynamic Ag+ (i.e., ionic colloidal silver) could play a pivotal role in overcoming cancerous processes. The authors of this white paper reviewed many of those findings and offer some dramatic case histories of cancers being cured in human test subjects.

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Potential Of Colloidal Or Silver Nanoparticles To Reduce The Growth Of B16F10 Melanoma Tumors

In this clinical study, published in the African Journal of Microbiology Research in March 2013, the researchers noted, “Previously, we reported the cytotoxic effect of colloidal silver on MCF-7 breast cancer cell line. However, there is scarce information on its antitumor potential. The aim of this study was to evaluate the anti-tumoral activity of colloidal silver or silver nanoparticles in a B16F10 melanoma mice model.”

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