Antifungal Effect of Silver Nanoparticles on Dermatophytes

Here’s an interesting clinical study demonstrating the effectiveness of silver nanoparticles against the pathogen most commonly responsible for toenail fungus. According to the study, “Spherical silver nanoparticles (nano-Ag) were synthesized and their antifungal effects on fungal pathogens of the skin were investigated.

Nano-Ag showed potent activity against clinical isolates and ATCC strains of Trichophyton mentagrophytes and Candida species. The activity of nano-Ag was comparable to that of amphotericin B, but superior to that of fluconazole. Additionally, we investigated their effects on the dimorphism of Candida albicans. The results showed nano-Ag exerted activity on the mycelia. Thus, the present study indicates nano-Ag may have considerable antifungal activity, deserving further investigation for clinical applications.”

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