Another Colloidal Silver Safety Study Finds No Toxicity

Another Colloidal Silver Safety Study Finds No Toxicity

By Steve Barwick, author, The Ultimate Colloidal Silver Manual

I’ve written in the past about two clinical studies using animals, both of which concluded that colloidal silver was non-toxic at the dosages used in the studies, which, by the way, were relatively high dosages in the thousands of ppm.

Now there’s a third animal study that I’ll tell you about in just a moment, which sought to discover whether or not colloidal silver was safe enough for use as a substitute for antibiotic drugs.

But first, let’s briefly review the findings from the first two studies, so we have a baseline to proceed from:

In this clinical study, published in 2013 in the journal Nanotoxicology, the researchers set out to help clarify potential health risks associated with silver nanoparticles (Ag-NPs).

Using commercially manufactured silver nanoparticles, the researchers evaluated silver’s potential genotoxicity (i.e., destructive effects on a cell’s genetic material), acute oral and dermal toxicity, eye irritation, dermal irritation and corrosion, and skin sensitization.

The silver nanoparticles were not found to induce genotoxicity (i.e., genetic harm) in a bacterial reverse mutation test and chromosomal aberration test, although some cytotoxicity was observed. (Editor’s note: Cytoxicity of silver nanoparticles would be considered normal when using bacterial cells, as silver is a broad-spectrum bactericide.)

In acute oral and dermal toxicity tests using rats, none of the rats showed any abnormal signs or mortality at a dose level of 2000 mg/kg (2,000 ppm).

Similarly, acute eye and dermal irritation and corrosion tests using rabbits revealed no significant clinical signs or mortality and no acute irritation or corrosion reaction for the eyes and skin.

In a skin sensitization test using guinea pigs, one animal (1/20) showed discrete or patchy erythema, thus Ag-NPs can be classified as a weak skin sensitizer.

In short, the researchers found that silver nanoparticles are:

  • Non-toxic to cells, with no mutations or chromosomal aberrations found.
  • When given orally, or applied topically, at a dosage of 2,000 mg/kg (i.e., 2,000 ppm), there were no abnormal signs.
  • When applied to the eyes and skin there were no abnormal signs.

The only minor negative sign was when one animal (of the twenty animals tested) developed a slight patch of red skin at the highest topical application. The red patch of skin turned out to be transient, meaning it faded away afterwards.

Let’s look at the second clinical study, which also used animals, but which more than doubled the dosage given to the animals in the previous study:

In this second clinical study, published in 2011 in the Journal of Veterinary Medical Science, another group of researchers tested mice for acute oral toxicity, eye irritation, corrosion and dermal toxicity of colloidal silver nanoparticles (AgNPs).

The findings were as follows:

  • Oral administration of colloidal silver nanoparticles at a limited dose of 5,000 mg/kg (i.e., 5,000 ppm) produced neither mortality nor acute toxic signs throughout the observation period.
  • The percentage of body weight gain of the mice showed no significant difference between control and treatment groups.
  • In the hematological analysis, there was no significant difference between mice treated with silver nanoparticles and controls.
  • Blood chemistry analysis also showed no differences in any of the parameter examined. There was neither any gross lesion nor histopathological change observed in various organs.
  • No gross abnormality was noted in the skins of the guinea pigs exposed to various doses of colloidal AgNPs. In addition, no significant AgNPs exposure relating to dermal tissue changes was observed microscopically.
  • In acute eye irritation and corrosion study, no mortality and toxic signs were observed when various doses of colloidal AgNPs were instilled in guinea pig eyes during 72 hr observation period. However, the instillation of AgNPs at 5,000 ppm produced transient eye irritation during early 24 hr observation time. (Recommendation: Don’t put 5,000 ppm strength colloidal silver into your eyes. Most people use 5-10 ppm colloidal silver for eye infections or other eye issues)

The researchers concluded, “In summary, these findings suggest that colloidal silver nanoparticles could be relatively safe when administered orally, or to the eyes and skin of the animal models for short periods of time.”

So that’s two separate animal studies demonstrating colloidal silver nanoparticles to be non-toxic at the relatively high dosages tested.

Let’s now take a look at the third and latest study:

Published in the EAS Journal of Pharmacy and Pharmacology in 2019, this third animal study sought to determine colloidal silver’s potential toxicology in relation to the idea of using it as a potential alternative to antibiotic drugs.

A typical 10 ppm commercial colloidal silver product called Colloidal Silver Life Water was used. 20 rats were divided into two groups. One group of rats got colloidal silver in place of their normal daily drinking water. The other group was given regular tap water for its daily drinking water.

Those were their only liquids given. And both groups of rats were allowed to drink their respective liquids ad libitum, meaning they could drink as much of the liquid as they wanted, for five days straight. The rats were also fed normally (i.e., grain) during the five day study.

After five days the animals were observed for clinical signs of toxicity.

Results: According to the researchers, no animals died during the study period. There were no signs of toxicity to the group of animals so freely given the colloidal silver water, nor to the group given the tap water.

In other words, during that five-day period in which half the rats were given colloidal silver in place of their drinking water, there was no more toxicity from the colloidal silver water than from plain old tap water. In terms of toxicity, they were both the same: No toxicity at all.

The researchers concluded, “The results indicate that Silver life Water can be regarded as virtually non-toxic in rats when given ad libitum for 5 days.”

Yes, the rats drank as much colloidal silver water as they wanted for five days, in place of their normal drinking water, and experienced no toxic effects.

The researchers further commented:

“Based on the toxicological report and literature review, the author of this research paper therefore recommends Colloidal Silver Water by Edigalf with a concentration of 10ppm which falls within the safe grade of the EPA to be taken 2 teaspoonful (10ml) three times (3x) daily which gives a power dose of 300mcg less than the 350mcg by the report.”

Put another way, the researchers believe, after extrapolating from their animal research, that it would be safe and non-toxic for humans to take 10 ppm colloidal silver at the rate of two teaspoonfuls, three times a day. This falls well within the dosage guidelines mentioned in various EPA reports on silver ingestion.

The researchers further concluded, “The most significant myth about silver is that it is neither safe nor effective for public consumption.”

In other words, the screaming headlines you might have read about colloidal silver being “risky” or “dangerous” are little more than myths. As long as it’s used responsibly, it’s safe and non-toxic. The animal studies demonstrate beyond any shadow of a doubt that in terms of toxicity, normal supplemental dosages of colloidal silver appear to be perfectly safe.

First Human Study

I’ve written about it before. But I’d be remiss if I didn’t mention once more that there’s also a peer-reviewed human clinical study demonstrating the safety and lack of toxicity of colloidal silver, which you can read about here:

This study was published in 2013 in the journal of Clinical Pharmacology & Therapeutics, and titled “An In Vivo Human Time-Exposure Investigation of a Commercial Silver Nano-Particle Solution.”

Seven different researchers from six different university research departments participated in the study of 36 healthy humans.

The humans were divided into three groups of 12 each, and given 15 mL per day of a commercial nanoparticle colloidal silver product, at 10 ppm and 32 ppm respectively, for three days, seven days and 14 days each.

Afterwards, at the end of each phase, they underwent extensive tests for:

  • Metabolic rate
  • Blood and platelet count
  • Urinalysis
  • Sputum hyper-responsiveness and inflammation evaluation
  • Physical examinations
  • Vital sign measurements

Plus, the researchers conducted magnetic resonance imaging (MRI) examinations of the chest and abdomen at baseline, and at the end of each phase.

According to the study authors:

“No clinically important changes in any metabolic, hematologic, or urinalysis measure identified were determined. No morphological (or structural) changes were detected in the lungs, heart (cardiac function) or abdominal organs. No changes were noted in sputum reactive oxygen species or in pro-inflammatory cytokines.”

In other words, no clinical signs of toxicity were found in this first-ever human safety study of oral colloidal silver usage!

So, for the first time ever, a human clinical study has conclusively demonstrated what’s already been known for the past 60-plus years from uncountable numbers of real-life examples of colloidal silver usage, i.e.:

Colloidal silver when properly made and responsibly used has one of the safest toxicological profiles of any nutritional supplement.

In contrast, prescription drugs, even when properly used, result in an average of 106,000 deaths per year, plus untold millions of adverse reactions and side effects, according to the Journal of the American Medical Association.

While the critics ignore the above data about the lack of toxicity of colloidal silver, and tout the very small handful of cases in which negative effects were attributed to colloidal silver after it was used abusively over long periods of time, they will now have to admit that responsible use of colloidal silver has no serious clinically discernible negative consequences.

C:\Users\Barwick\AppData\Local\Microsoft\Windows\Temporary Internet Files\Content.Word\44373021_s.jpgImportant Addendum: Where to Find Colloidal Silver

If you’re brand new to colloidal silver usage and are wondering where to buy it, it’s important to know that you can find it in just about any well-stocked health food store in America.  It’s also available on Amazon and numerous other websites.

But it can be extremely expensive. In fact, because colloidal silver works so well against numerous forms of infection and disease, it has the highest price mark-up of any nutritional supplement in existence.

The amount of actual silver in a four-ounce bottle of colloidal silver is about five to 12 cents worth.  (Yes, I said five to twelve cents.)

Yet because that small amount of silver is all it takes to decimate so many different kinds of infections, the manufacturers mark it up about 16,000%, charging a whopping $20 or $30 per bottle.

What’s more, manufacturers promoting the latest faddish colloidal silver product often charge far more per bottle – sometimes $35 to $50 for a tiny four-ounce bottle.

And people are more than willing to pay through the nose for these commercial colloidal silver products at health food stores because colloidal silver does indeed heal infections and prevent the spread of germs and disease faster and better than any other natural supplement on the planet!

So, commercially speaking, the retail price of colloidal silver at health food stores reflects its value to the consumer far more so than its true cost to produce. But here’s the good news:


Make Your Own High-Quality
Colloidal Silver for Pennies!

As I mentioned, typical health food store prices for colloidal silver can range from $20 to $30 for a tiny, four-ounce bottle.

But with a brand new Micro-Particle Colloidal Silver Generator from The Silver Edge, you can make your own safe, pure, high-quality micro-particle colloidal silver for about 36 cents a quart!  In other words, you can make it at actual cost, just like the big colloidal silver bottlers do.

Compared to typical health food store prices, your first two one-quart batches literally pay for the entire cost of your new generator!  Do you know of any other health product that literally pays for itself the very first few times you use it? The savings are absolutely astonishing!

In fact, by making your own high-quality colloidal silver with a brand new Micro-Particle Colloidal Silver Generator from The Silver Edge, you’ll be as close to having FREE colloidal silver as you can get, and for the rest of your life!

You’ll never have to pay those exorbitant health food store prices again!

The new Micro-Particle Colloidal Silver Generator is now the world’s #1 best-selling colloidal silver generator. Here are just a few reasons why you should own one…

  • It pays for itself after your very first batch or two — your total cost to make your first one-quart batch is about 36 cents, compared to the $240 you’d pay at a health food store if you bought an equivalent amount (i.e., eight of those little 4-ounce bottles they normally sell for $30 apiece)!
  • Safe, simple to operate…No special skills needed…You just set the handy timer, plug it in, walk away, and three hours later you have a perfect batch of therapeutic quality micro-particle colloidal silver…every time!  Here’s a short pictorial demonstrating how astonishingly easy it is to use a new Micro-Particle Colloidal Silver Generator from The Silver Edge:

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  • Produces uncommonly small silver micro-particles as low as .8 nm. That’s a fraction of a single nanometer. Compare that to health food store colloidal silver which can contain silver particles as large as 200 nm to 1,000 nm (or even larger), and you’ll see why micro-particle colloidal silver is the very best there is!  Smaller particles mean your body can absorb and utilize up to 99% of the colloidal silver you take, compared to maybe 30% or 40% with many health food store brands!
  • Runs on standard household electricity, but uses less power than a tiny Christmas tree bulb – you won’t even see a blip on your electric bill!
  • Produces uniform, crystal clear batches every single time that store for months, or even years, without losing potency!
  • Cannot produce silver chloride or unsafe substances – you get pure, therapeutic-quality micro-particle colloidal silver every time!

Just read through some of the testimonials below to see for yourself how you’ll save literally thousands of dollars per year by making your own colloidal silver with your brand new Micro-Particle Colloidal Silver Generator from The Silver Edge!

Customer Testimonials

Here’s what one customer recently wrote to tell us:

“Owning a Micro-Particle Colloidal Silver Generator from The Silver Edge has given us the luxury of being able to use high-quality colloidal silver any time we need it.  And we never have to worry about the costs because it only costs a few pennies per quart to make!  It is without a doubt the single-best money-saving appliance in my entire house!

Best of all, the machine is very easy to use, and easy to store. I was concerned about ease-of-use, but my fears were unfounded. After I got mine and used it, I immediately bought one and sent it to my 83 year old mom, and she uses it regularly as well.

Now that I have a Micro-Particle Colloidal Silver Generator, I can use colloidal silver for everything — disinfecting the kitchen sinks, countertops, and the cutting board… spraying the toilet bowls, and the bathroom countertops and sinks… spraying it on my toothbrush to prevent bacterial growth…rinsing my mouth with it to prevent cavities and gum disease…you name it.

I even put it in the laundry rinse cycle when I do my linens, towels and kitchen rags, so I don’t have to wash them as frequently. It really keeps them fresh, and there’s never any mold or mildew anywhere in our house.

I also put some in the cat’s water bowl each day, and the dog’s too.  We use it in the bathtub for skin problems.  And of course we drink it when our tummies are queasy, or when we feel a cold or flu coming on.  We also gargle with it in order to get rid of sore throats, and sniff it up our noses to get rid of sinus problems.

My husband even sprays it on his hair in the mornings, and has completely eliminated his lifelong dandruff problem.  And he sprays a little bit in his eyes from time to time, and now has no more recurrent problems with sties.”

— K. Sullivan, NM

And here’s what another happy customer wrote to say about the tremendous savings she’s achieved by no longer having to purchase her colloidal silver through health food stores:

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“We make a quart of colloidal silver at least once a week with the Micro-Particle Colloidal Silver Generator from the Silver Edge. I finally sat down and figured out how much this machine has been saving us. By making our own colloidal silver we’ve saved $11,503.20 this year alone, compared to the cost of colloidal silver at our local health food store.

The cost for colloidal silver at our local health food store is $30 for a tiny four-ounce bottle. But with my Micro-Particle Colloidal Silver Generator, I can make eight times that amount (i.e., a full quart) for about 35 cents total cost.

If I were to purchase a quart of colloidal silver at the health food store, which would be eight of those tiny, four-ounce bottles, the cost would be a whopping $240 (i.e., 8 x $30 = $240) compared to the 35 cents I now spend to make a full quart!

Here’s the breakdown of our costs to make a full quart of colloidal silver with our Micro-Particle Colloidal Silver Generator: It costs us about a dollar for a gallon of steam-distilled water at Walmart. So a quart of the steam-distilled water costs about 25 cents. And I estimate we use maybe a nickel’s worth of electricity and maybe another nickel’s worth of silver from the silver rods for every one-quart batch of colloidal silver we make. So that’s 35 cents a quart, all told, for each quart of micro-particle colloidal silver we make!

And frankly, considering how long the .999 fine silver rods have lasted (over a year and a half, so far, for the most recent set), I think it’s probably even cheaper than that. But it’s the lifetime savings we’ve experienced that’s just mind-boggling to me.

For example, we’ve had our Micro-Particle Colloidal Silver unit for nearly five years now. And as I mentioned we make one quart per week, and we spend about 35 cents a week on making colloidal silver.

This means we save about $239.65 a week by not having to purchase a quart’s worth of colloidal silver at our local health food store.  So do the math: In just one month, the savings is $958.60…in one year, the savings is $11,503.20…and in five years we’ve saved approximately $57,516.00!

When you put pencil to paper and figure it out, it definitely takes you by surprise. You just think ‘No way. I must have multiplied that wrong.’

But it’s true. The savings is legitimately well over $11,000 a year over health food store prices for colloidal silver, if you make and use a quart of colloidal silver a week like we do!  And we reap that incredible savings from the very reasonable $250 investment we made in purchasing our Micro-Particle Colloidal Silver Generator.

In their advertising literature, The Silver Edge says the unit completely pays for itself after your first couple of one-quart batches. But really, that’s quite an understatement when you realize the true extent of your savings!

Of course, once you start making your own colloidal silver with a Micro-Particle Colloidal Silver Generator from The Silver Edge, you don’t really think about how much you’re saving compared to health food store prices, because it just becomes a normal part of your everyday life. But the savings is nevertheless astonishing when you reflect on it.

What’s especially nice is being able to produce a significantly higher-quality colloidal silver than what’s generally available to the public through health food stores, especially at such a tiny, tiny fraction of the cost.”

— Marie Wilkey, SC

The Bottom Line…

With a high-quality Micro-Particle Colloidal Silver Generator from The Silver Edge, you’ll never again have to pay exorbitant health food store or internet vendor prices for high-quality colloidal silver!

Indeed, your first batch or two will indeed completely pay for the entire cost of your generator, compared to health food store prices!

What’s more, you’ll be able to give colloidal silver away FREE to family members, friends and neighbors, because you’ll be making it — literally — for only a few pennies per batch!

Simply click on this link to learn more about this phenomenal new breakthrough in colloidal silver-making technology, including our current, time-limited, money-saving offers that can save you up to $100 if you act quickly and decisively!

Meanwhile, I’ll be back next week with another insightful article on colloidal silver….

Yours for the safe, sane and responsible use of colloidal silver,


Steve Barwick, author

The Ultimate Colloidal Silver Manual

Helpful Links:

FREE Colloidal Silver Safe Dosage Report

Colloidal Silver Secrets Group on Facebook

Make Your Own Colloidal Silver for Pennies

.999 Pure Silver Wire for Making Colloidal Silver

Important Note and Disclaimer: The contents of this Ezine have not been evaluated by the Food and Drug Administration. Information conveyed herein is from sources deemed to be accurate and reliable, but no guarantee can be made in regards to the accuracy and reliability thereof. The author, Steve Barwick, is a natural health journalist with over 30 years of experience writing professionally about natural health topics. He is not a doctor. Therefore, nothing stated in this Ezine should be construed as prescriptive in nature, nor is any part of this Ezine meant to be considered a substitute for professional medical advice. Nothing reported herein is intended to diagnose, treat, cure or prevent any disease. The author is simply reporting in journalistic fashion what he has learned during the past 17 years of journalistic research into colloidal silver and its usage. Therefore, the information and data presented should be considered for informational purposes only, and approached with caution. Readers should verify for themselves, and to their own satisfaction, from other knowledgeable sources such as their doctor, the accuracy and reliability of all reports, ideas, conclusions, comments and opinions stated herein. All important health care decisions should be made under the guidance and direction of a legitimate, knowledgeable and experienced health care professional. Readers are solely responsible for their choices. The author and publisher disclaim responsibility and/or liability for any loss or hardship that may be incurred as a result of the use or application of any information included in this Ezine.

Copyright 2019 | Life & Health Research Group, LLC | PO Box 1239 | Peoria AZ 85380-1239 | All rights reserved.



Click the image above to learn more about the Micro-Particle Colloidal Silver Generator that allows you to make high-quality colloidal silver for less than 36 cents a quart, and is so easy to use, even my 88 year old mom uses one!

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Phoenix, AZ 85071

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[IMPORTANT NOTE AND DISCLAIMER: We are not doctors. We are distributors of electronic appliances and nutritional supplements. Therefore we cannot and do not offer medical advice. Please do not call with medical questions. If you have a medical problem, please see your licensed physician. Self-treatment is not recommended. The FDA has not evaluated the information contained on this web site. Products distributed by The Silver Edge are not intended to diagnose, treat, cure or prevent any disease. Testimonials are the subjective experiences of our customers and are not intended to be construed as being prescriptive in nature, nor a guarantee that the usage methods described are safe, effective or reliable, nor a guarantee that your results will be the same; individual results may vary. Additionally, the contents of this web site are strictly for information purposes only, and should not in any way be construed as providing or attempting to provide medical advice. Information on this web site is derived from sources deemed to be accurate and reliable, but no guarantee, express or implied, can be made regarding the accuracy or reliability of same. Therefore readers are encouraged to verify for themselves and to their own satisfaction the accuracy and reliability of all reports, recommendations, conclusions, comments, and opinions. The Silver Edge does not make any claims or promises as to health benefits accruing from the use of any product. There is plenty of publicly available independent documentation -- both pro and con -- regarding the uses and efficacy of colloidal silver and its long history in health and medicine. For a comprehensive overview, you may want to obtain a copy of The Ultimate Colloidal Silver Manual (547 pages, from Life & Health Research Group, LLC, 1-888-846-9029). Or see the link above to "Some Interesting Sources of Information on Colloidal Silver." Colloidal silver generators are electronic appliances designed to produce high-quality silver colloid. They are not medical devices. The Silver Edge specifically disclaims responsibility or liability for any loss or hardship that may be incurred by the reader as a result of the application of any information included on this web site, or as a result of the use or misuse of any electronic product or nutritional supplement. You are solely responsible for your health and nutrition choices. Anyone with additional information on colloidal silver is encouraged to write to The Silver Edge at the address directly below, so that it can be shared with others who may be interested.]